Announcing: Nitisinone Different Age Groups of Patients with Alkaptonuria

The study is designed to treat patients and find the optimal dosage of nitisinone to obtain maximal reduction in levels of homogentisic acid and maintain safe levels of tyrosine. The long term objective in the target population of pre-symptomatic patients is the prevention of the characteristic effects on joint cartilage and tendons.

Clinical trial sponsored by University of California, San Diego